Fig. 8

Apoptotic and necrotic cell death were assessed using Annexin V and Probidium Iodide (PI) staining and analyzed using flow cytometer after 24 h treatment with azetidinone derivatives. a MDA-MB-231 cells control (DMSO), b MDA-MB-231 cell treated with 105 µg/mL of 6c, c MDA-MB-231 cell treated with 170 µg/mL of 6d, d MDA-MB-231 cell treated with 130 µg/mL of 6k, and e quantification of apoptotic and necrotic cell death for each drug on MDA-MB-231 cells