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Table 2 pMIC values (μM/mL) of synthesized naringenin derivatives against different standard microbial strains

From: Naringenin derivatives as glucosamine-6-phosphate synthase inhibitors: synthesis, antioxidants, antimicrobial, preservative efficacy, molecular docking and in silico ADMET analysis

Compound(s)

PMIC values in μM/mL

P. mirabilis

P. aeruginosa

S. aureus

E. coli

C. albicans

A. niger

Compound 1

1.79

1.79

1.49

1.49

1.49

1.49

Compound 2

1.14

1.14

0.83

1.14

1.14

0.83

Compound 3

0.86

1.16

0.86

0.86

1.16

1.46

Compound 4

1.18

0.88

0.88

1.18

0.88

1.18

Naringenin

< 0.73

< 0.73

< 0.73

< 0.73

< 0.73

< 0.73

Streptomycin

1.06

1.36

1.06

1.96

–

–

Ciprofloxacin

1.12

1.42

1.12

1.42

–

–

Ampicillin

1.14

0.84

0.84

1.74

–

–

Fluconazole

–

–

–

–

1.08

1.38

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BMC Chemistry

ISSN: 2661-801X

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