Magnetic γFe2O3@Sh@Cu2O: an efficient solid-phase catalyst for reducing agent and base-free click synthesis of 1,4-disubstituted-1,2,3-triazoles

Table 3 Scope of reaction of benzyl halides with alkynes and sodium azide catalyzed by magnetic γFe₂O₃@Sh@Cu₂O

Entry	R¹	R²	Product	Isolated yield %	Time (min)	TON	TOF (h⁻¹)	M.p [refs.]
1	H	H	4a	93	20	3.5 * 10⁵	1.0 * 10⁶	125–127 [9]
2	H	4-Me	4b	77	20	2.9 * 10⁵	8.8 * 10⁵	147–148 [44]
3	H	4-OMe	4c	97	25	3.7 * 10⁵	8.9 * 10⁵	138–140 [20]
4	4-Br	H	4d	98	20	3.7 * 10⁵	7.5 * 10⁵	147–149 [22]
5	4-Br	4-Me	4e	72	20	2.7 * 10⁵	8.3 * 10⁵	165–167 [45]
6	4-Br	4-OMe	4f	98	20	3.7 * 10⁵	1.1 * 10⁶	164–166 [24]
7	4-OMe	H	4g	73	20	2.8 * 10⁵	8.4 * 10⁵	125–127 [46]
8	4-OMe	4-Me	4h	57	20	2.1 * 10⁵	8.2 * 10⁵	132–135 [20]
9	4-OMe	4-OMe	4i	66	20	2.5 * 10⁵	7.6 * 10⁵	98–100 [47]
10	4-NO₂	H	4j	53	25	2.0 * 10⁵	6.1 * 10⁵	152–154 [48]
11	4-NO₂	4-Me	4k	50	25	1.9 * 10⁵	5.7 * 10⁵	242–245 [49]
12	4-NO₂	4-OMe	4l	70	25	2.6 * 10⁵	6.4 * 10⁵	123.5–125.5 [50]
13	2-Cl	H	4m	88	20	3.3 * 10⁵	8.1 * 10⁵	84–86 [9]
14	2-Cl	4-Me	4n	88	20	3.3 * 10⁵	8.1 * 10⁵	117–118 [23]
15	2-Cl	4-OMe	4o	75	20	2.8 * 10⁵	3.4 * 10⁵	137–138^a

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