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Table 1 Cytotoxic activities of tested compounds against liver carcinoma cell line (HEPG2)
figurea

From: Facile synthesis and antiproliferative activity of new 3-cyanopyridines

Compd no.RR′IC50 (μM)
Doxorubicin0.72
5aC6H5 22.3
5b4-MeC6H440.9
5c 1.46
5d 7.08
9aC6H5 42.8
9b4-MeC6H465.3
9c 23.9
9d 66.5
13aC6H574.3
13b4-MeC6H492.5
13c 39.0
13d 72.4
  1. The most active compounds are in italic