Table 2 Preparation of tetrahydrobenzo[b]pyran derivatives in water as solvent using MWI
From: A facile and one-pot synthesis of new tetrahydrobenzo[b]pyrans in water under microwave irradiation
Entry | R | Product | Yield (%) |
|---|---|---|---|
1a | 4-OMe | 4a | 96 |
1b | 3-OMe | 4b | 92 |
1c | 4-F | 4c | 94 |
1d | 2,5-(OMe)2 | 4d | 90 |
1e | 2-Br | 4e | 93 |
1f | 2-CF3 | 4f | 89 |
1g | 2-OMe | 4 g | 98 |
1h | 2-NO2 | 4 h | 94 |
1i | 2-Cl | 4i | 89 |
1j | 2-F | 4j | 92 |
1k | 3-Pyridinyl | 4k | 95 |