Table 1 Preparation of five bisarylic compounds 
From: gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect
Compound | X | R1 | R2 |
|---|---|---|---|
A1 | C=O |
| –CO2CH3 |
A2 | CF2 |
| –CO2CH3 |
A3 | CF2 | Br | –CO2H |
A4 | CF2 | –COCH3 | –CO2H |
A5 | CF2 | –CH(CH3)2 | –CO2H |
