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Table 8 Docking Scores of first three best docked posses of Compound 2a, 2b, 2d and 2g with UDP-N-acetylmuramate/l-alanine ligase

From: Designing, synthesis and characterization of 2-aminothiazole-4-carboxylate Schiff bases; antimicrobial evaluation against multidrug resistant strains and molecular docking

Target protein Compound Ligand modes Binding affinity rmsd/ub rmsd/lb
UDP-N-acetylmuramate/l-alanine ligase 2a 0 − 6.8 0 0
2a 1 − 6.7 28.075 26.052
2a 2 − 6.6 28.511 26.881
2b 0 − 7.6 0 0
2b 1 − 7.0 28.764 27.311
2b 2 − 7.0 28.373 27.402
2d 0 − 7.3 0 0
2d 1 − 7.0 28.595 27.20
2d 2 − 7.0 28.136 26.504
2g 0 − 7.1 0 0
2g 1 − 6.9 7.342 2.41
2g 2 − 6.8 3.16 2.568
  1. UDP uridine diphosphate