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Table 2 Antibiotic resistance profiling

From: Designing, synthesis and characterization of 2-aminothiazole-4-carboxylate Schiff bases; antimicrobial evaluation against multidrug resistant strains and molecular docking

Antibiotics Zone of inhibition (mm)
Gram Negative bacteria Gram Positive bacteria CLSI guideline
Escherichia coli Pseudomonas aeruginosa Staphylococcus epidermidis Staphylococcus aureus S I R
Cefepime 9 15 – – ≥ 18 15–17 ≤ 14
Ciprofloxacin No zone 20 20 22 ≥ 21 16–20 ≤ 15
Imipenem 20 18 – – ≥ 23 20–22 ≤ 19
Cefoxitin 17 No zone 14 15 ≥ 18 15–17 ≤ 14
Ampicillin No zone No zone 18 No zone ≥ 17 14–16 ≤ 13
Aztreonam 12 17 No zone No zone ≥ 21 18–20 ≤ 17
Tetracycline 8 No zone No zone 18 ≥ 15 12–14 ≤ 11
Ceftazidime 10 14 – – ≥ 21 18–20 ≤ 17
Minocyclin 13 13 – 18 ≥ 19   ≤ 14
Gentamycin No zone 18 16 18 ≥ 15 13–14 ≤ 12
Co-trimoxazole No zone 12 No zone 15 ≥ 16 11–15 ≤ 10
Colistin 9 12 No zone No zone ≥ 11   ≤ 10
Clindamycin No zone No zone No zone No zone ≥ 21 15–20 ≤ 14
Vancomycin No zone No zone No zone 15 ≥ 22   ≤ 21
Doxicyclin 12 12 – 18 ≥ 16   ≤ 12
Erythromycin 7 No zone No zone 20 ≥ 23 14–22 ≤ 13
Chloramphenicol – – 23 20 ≥ 32 16 ≤ 8
  1. Susceptible (S), intermediate (I) and resistant (R)
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