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Table 4 Statistical comparison for the results obtained by the proposed spectrophotometric methods and the reported method for the analysis of PAR and IBUin pure powder form

From: Three smart spectrophotometric methods for resolution of severely overlapped binary mixture of Ibuprofen and Paracetamol in pharmaceutical dosage form

Value RD PAR RD IBU
MCR CC Reported methoda [5] MCR CC Reported methoda [5]
Mean 99.95 99.91 99.64 100.25 100.14 100.18 99.97 99.63
SD 0.34 0.65 0.803 0.54 0.81 0.78 0.641 0.65
RSD% 0.340 0.650 0.806 0.538 0.808 0.778 0.641 0.652
n 5 5 5 5 5 5 5 5
Variance 0.115 0.422 0.645 0.291 0.656 0.608 0.411 0.422
Student’s t test(2.306) 1.036 0.1609 1.412   1.096 0.7081 0.834  
F-value(6.388) 2.136 1.690 2.216   1.417 5.382 1.027  
  1. The values in the parenthesis are the corresponding theoretical values of t and F at P = 0.05
  2. aSpectrophotometric method using derivative of the ratio spectra method