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Table 4 IC50 (µg ml−1) of synthesized diazenyl chalcones against A549 and HEK cell line

From: Antimicrobial, antioxidant and cytotoxic evaluation of diazenyl chalcones along with insights to mechanism of interaction by molecular docking studies

Compound A549
IC50 (µg ml−1)
HEK
IC50 (µg ml−1)
Ratio (HEK/A549)
IC50 (µg ml−1)
C-19 140.17 ± 1.11 221.06 ± 3.23 1.58
C-22 156.45 ± 1.23 296.45 ± 2.32 1.90
C-23 171.31 ± 2.46 190.11 ± 1.56 1.11
C-24 108.89 ± 3.21 280.45 ± 1.21 2.59
C-25 18.01 ± 1.34 270.23 ± 2.82 15.00
C-27 123.52 ± 2.56 330.56 ± 2.90 2.67
Std 8.7 9.0 [28] 1.03
  1. Std camptothecin, A549 human lung cancer cell line, HEK human embryonic kidney cells