Table 9 Anticancer activity results of compounds (12a and 12b)
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
Compounds | Cancer cell lines (IC50 = µM) | ||||
|---|---|---|---|---|---|
HeLa | MiaPaCa-2 | SW 620 | MCF-7 | H 460 | |
12a | 0.8 ± 0.4 | 4 ± 2 | 30 ± 5 | 13 ± 3 | 26 ± 13 |
12b | 0.7 ± 0.2 | 4 ± 2 | 25 ± 4 | 11 ± 1 | 22 ± 2 |
Cisplatin | 3 ± 0.6 | 4 ± 3 | 4 ± 1 | 12 ± 6 | 0.3 ± 0.04 |
Doxorubicin | 0.04 ± 0.009 | 0.01 ± 0.01 | 0.02 ± 0.01 | 0.04 ± 0.01 | Not tested |