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Table 9 Anticancer activity results of compounds (12a and 12b)

From: Benzimidazole scaffolds as promising antiproliferative agents: a review

Compounds Cancer cell lines (IC50 = µM)
HeLa MiaPaCa-2 SW 620 MCF-7 H 460
12a 0.8 ± 0.4 4 ± 2 30 ± 5 13 ± 3 26 ± 13
12b 0.7 ± 0.2 4 ± 2 25 ± 4 11 ± 1 22 ± 2
Cisplatin 3 ± 0.6 4 ± 3 4 ± 1 12 ± 6 0.3 ± 0.04
Doxorubicin 0.04 ± 0.009 0.01 ± 0.01 0.02 ± 0.01 0.04 ± 0.01 Not tested