Table 27 Anticancer activity results of synthesized compounds (42a–42c)
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
Compounds | Cancer cell lines (EC50 (µM)) | |||
|---|---|---|---|---|
SKOV-3 | A375 | MCF-7 | A549 | |
42a | 17 ± 7 | 5 ± 2 | 12 ± 1 | > 50 |
42b | 33 ± 5 | 12 ± 2 | 29 ± 8 | > 50 |
42c | 41 ± 13 | 13 ± 2 | 17 ± 3 | 45 ± 3 |
Auphen | 7.00 ± 2.00 | 1.7 ± 0.3 | 3.00 ± 0.05 | 1.07 ± 0.09 |