Table 18 Cytotoxicity and tubulin polymerization inhibition of compound 33a
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
Compound | Cancer cell lines (GI50 µM) | Inhibition of tubulin polymerization | ||
|---|---|---|---|---|
HepG2 | A549 | MCF-7 | (IC50 µM) | |
33a | 3.8 | 2.4 | 5.1 | 1.5 |
CA-4 | 7.4 | 2.8 | 9.4 | 1.8 |
Colchicine | 10.5 | 4.4 | 13.5 | 2.62 |