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Table 18 Cytotoxicity and tubulin polymerization inhibition of compound 33a

From: Benzimidazole scaffolds as promising antiproliferative agents: a review

Compound Cancer cell lines (GI50 µM) Inhibition of tubulin polymerization
HepG2 A549 MCF-7 (IC50 µM)
33a 3.8 2.4 5.1 1.5
CA-4 7.4 2.8 9.4 1.8
Colchicine 10.5 4.4 13.5 2.62