Table 10 Percentage growth inhibitory value of compound 19a
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
| Cancer cell lines | Compound 19a | 5-Fluorouracil | |
|---|---|---|---|
| Leukemia | |||
| HL-60 (TB) | 80.51 | 47.9 | |
| CCRF-CEM | 72.52 | 57.1 | |
| K-562 | 57.34 | 42.3 | |
| MOLT-4 | 38.03 | 43.1 | |
| RPMI-8226 | 46.65 | 41.4 | |
| Breast tumor | |||
| T-47D | 70.68 | 56.7 | |
| MDA-MB231/ATCC | 58.91 | 78.1 | |
| MDA-MB-468 | 48.37 | Not tested | |
| BT-549 | 33.10 | 37.8 | |
| Colon tumor | |||
| HCT-116 | 62.25 | 17.8 | |
| HCT-15 | 72.67 | 26.5 | |
|
Melanoma cancer LOX IMVI | 54.29 | 30.4 | |
|
Prostate cancer PC-3 | 56.69 | 58.2 | |