Table 1 Percentage growth inhibition of compound 2a
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
Compound | Conc. (µM) | Cancer cell lines | |||
|---|---|---|---|---|---|
% Growth inhibition | |||||
MCF-7 | THP-1 | PC-3 | A-549 | ||
2a | 10 | 36 | 39 | 42 | 30 |
50 | 93 | 68 | 60 | 70 | |
100 | 96 | 71 | 81 | 89 | |
Adriamycin | 1 | 72 | – | – | – |
Paclitaxel | 1 | – | – | – | 65 |
Mitomycin | 1 | – | – | 61 | – |
5-FU | 20 | – | 67 | – | – |