Table 2 Antimicrobial activity of newly synthesized compounds (S1–S18)
Compound | Minimum inhibitory concentration (MIC = µM/ml) | |||||
|---|---|---|---|---|---|---|
Bacterial species | Fungal species | |||||
S. aureus | B. subtilis | E. coli | S. typhi | A. niger | C. albicans | |
S 1 | 0.81 | 0.81 | 0.81 | 0.81 | 3.26 | 3.26 |
S2 | 3.19 | 3.19 | 1.59 | 1.59 | 3.19 | 3.19 |
S3 | 3.49 | 3.49 | 3.49 | 3.49 | 3.49 | 3.49 |
S 4 | 3.64 | 3.64 | 3.64 | 3.64 | 0.91 | 0.91 |
S5 | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 |
S6 | 3.48 | 3.48 | 3.48 | 3.48 | 1.74 | 1.74 |
S7 | 3.35 | 3.35 | 6.70 | 6.70 | 3.35 | 3.35 |
S8 | 3.19 | 3.19 | 3.19 | 3.19 | 3.19 | 3.19 |
S9 | 3.59 | 3.59 | 3.59 | 3.59 | 3.59 | 3.59 |
S10 | 3.49 | 3.49 | 3.49 | 3.49 | 3.49 | 3.49 |
S11 | 0.87 | 1.74 | 3.49 | 3.49 | 3.49 | 6.98 |
S12 | 3.99 | 3.99 | 3.99 | 3.99 | 3.99 | 3.99 |
S13 | 3.51 | 3.51 | 3.51 | 3.51 | 3.51 | 3.51 |
S14 | 3.79 | 3.79 | 3.79 | 3.79 | 3.79 | 3.79 |
S15 | 3.79 | 3.79 | 7.59 | 7.59 | 7.59 | 3.79 |
S16 | 3.79 | 3.79 | 3.79 | 3.79 | 3.79 | 3.79 |
S17 | 3.64 | 7.28 | 3.64 | 3.64 | 3.64 | 3.64 |
S18 | 6.70 | 3.35 | 3.35 | 3.35 | 3.35 | 3.35 |
Cefadroxil | 1.64 | 3.28 | 1.64 | 1.64 | ||
Fluconazole | 2.04 | 2.04 | ||||