Synthesis of thiophene derivatives and their anti-microbial, antioxidant, anticorrosion and anticancer activity

BMC Chemistry

Table 1 The physicochemical properties of newly synthesized derivatives (S₁–S₁₈)

Compound	M. formula	M. Wt.	m. p. (°C)	R_f value^a	% Yield
S ₁	C₁₈H₁₇Cl₂NO₂S	382.30	96–97	0.53	84.71
S ₂	C₁₈H₁₈BrNO₂S	392.31	122–124	0.47	75.00
S ₃	C₁₈H₁₈N₂O₄S	358.41	87–89	0.62	82.22
S ₄	C₁₉H₂₁NO₃S	343.44	95–98	0.38	72.67
S ₅	C₂₂H₂₈N₂O₂S	384.53	98–100	0.39	78.86
S ₆	C₁₉H₂₁NO₄S	359.44	95–97	0.66	82.43
S ₇	C₂₀H₂₃NO₄S	373.13	97–99	0.45	83.67
S ₈	C₁₈H₁₈BrNO₂S	392.31	94–95	0.42	87.62
S ₉	C₁₈H₁₈ClNO₂S	347.86	87–88	0.41	85.63
S ₁₀	C₁₈H₁₈N₂O₄S	358.41	94–97	0.61	79.80
S ₁₁	C₁₈H₁₈N₂O₄S	358.41	130–131	0.58	72.58
S ₁₂	C₁₈H₁₉NO₂S	313.41	90–93	0.31	68.72
S ₁₃	C₂₀H₂₄N₂O₂S	356.48	134–135	0.53	83.23
S ₁₄	C₁₈H₁₉NO₃S	329.41	110–111	0.68	73.65
S ₁₅	C₁₈H₁₉NO₃S	329.41	108–109	0.63	81.35
S ₁₆	C₁₈H₁₉NO₃S	329.41	93–94	0.56	69.87
S ₁₇	C₁₈H₁₉NO₃S	343.44	93–95	0.55	81.81
S ₁₈	C₂₀H₂₃NO₄S	373.13	97–99	0.62	76.69

ISSN: 2661-801X