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Table 1 Mean zone of inhibition beyond well diameter (6 mm) produced on a range of clinically pathogenic microorganisms using a 5 mg/mL concentration of tested samples

From: Utility of 5-(furan-2-yl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide in the synthesis of heterocyclic compounds with antimicrobial activity

Compound no.

Microorganisms

Fungi

Gram-Positive Bacteria

Gram-Negative Bacteria

AF

CA

SP

BS

PA

EC

3

16.2

12.5

16.8

14.6

12.1

12.8

4

15.7

13.2

10.5

13.6

12.6

11.2

10a

12.6

11.2

0

0

0

0

10b

17.3

16.9

17.3

18.3

18.3

22.6

11a

21.2

19.6

23.8

23.8

17.3

19.9

11b

15.7

13.3

0

0

0

0

12a

18.9

15.4

15.7

14.1

10.8

11.1

12b

16.7

18.1

16.7

21.1

10.7

9.9

13

19.1

16.9

13.6

14.7

12.1

10.4

14

15.7

14.1

17.2

14.9

15.2

17.2

15

16.4

12.7

19.9

18.4

11.6

10.9

20a

20.8

16.8

13.1

10.8

13.4

12.3

20b

26.8

15.3

11.2

12.7

9.8

11.3

20c

15.9

17.1

18.7

15.4

11.7

10.3

20d

20.6

15.8

18.9

12.7

11.3

9.9

21a

17.7

18.2

19.2

15.4

10.2

8.8

21b

19.1

18.9

17.3

17.7

0

9.9

22

23.8

32.4

13.2

13.3

0

10.2

23

18.8

15.6

17.9

13.3

11.4

10.7

25a

18.4

16.3

12.6

13.2

10.1

10.9

25b

0

0

12.7

14

9.7

8.3

Amphotericin B

23.7

25.4

–

–

–

–

Ampicillin

–

–

23.8

32.4

–

–

Gentamicin

–

–

–

–

17.3

19.9