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Table 3 In silico ADME and physicochemical parameters analysis of selected compounds are shown

From: Docking predictions based Plasmodium falciparum phosphoethanolamine methyl transferase inhibitor identification and in-vitro antimalarial activity analysis

S. no. Structure and zinc id RV S S A Al P
1 0 − 2.6 3 1.5 0 114.7
2 0 − 3.7 3 2.7 0 99.8
3 0 − 3.6 3 2.8 0 107.1
4 0 − 3.3 3 2.0 0 104.8
5 0 − 3.0 3 2.5 0 94.7
  1. (ALogp98) value should range between the − 2.0 and 5.0 and PSA should not be more than 140 A for good intestinal absorption (as per Lipinski rule)
  2. RV rule of violation, S solubility, SL solubility level, A AlogP98, AL absorption level, P PSA