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Table 2 Calculated pIC50, Z-score, and predicted pIC50 for the data set for building the QSAR model

From: QSAR-based rational discovery of novel substituted-4′-iminospiro[indoline-3,3′-[1,2,5]thiadiazolidinyl]-2-one 1′,1′-dioxide with potent in vitro anticancer activity

Compound IC50 (μM) pIC50 Residual Z-score Predicted pIC50
I 0.85 6.070 0.0000 0.1116 6.07
II 0.28 6.552 0.0001 0.1684 6.55
III 0.38 6.420 0.0001 0.2929 6.42
IV 1.2 5.920 0.0001 0.2873 5.92
V 3.2 5.494 0.0001 0.4187 5.44
VI 0.57 6.244 0.0005 1.6129 6.24
VII 0.57 6.244 0.0006 1.7125 6.24
VIII 0.64 6.193 0.0007 2.2621 6.19
IX 0.63 6.200 0.0003 0.8417 6.20
X 0.39 6.408 0.0003 0.9366 6.40
XI 1.34 5.872 0.0000 0.0055 5.87
XII 0.28 6.552 0.0004 1.1437 6.55
XIII 0.18 6.744 0.0001 0.4482 6.74
XIV 0.13 6.886 0.0005 1.3919 6.88
XV 0.28 6.552 0.0004 1.1742 6.55
XVI 0.075 7.124 0.0004 1.1085 7.12
XVII 0.11 6.958 0.0003 0.5351 6.96
XVIII 0.25 6.602 0.0002 1.0190 6.60