Compounds | Minimum inhibitory concentration (MIC = μM) | IC50 (μM) | ||||
---|---|---|---|---|---|---|
Bacterial species | Fungal species | Cancer cell line (HCT116) | ||||
Gram +ve | Gram −ve | |||||
SA | ST | KP | CA | AN | ||
W1 | 10.15 | 10.15 | 10.15 | 5.08 | 5.08 | > 20.31 |
W2 | 11.17 | 11.17 | 11.17 | 5.59 | 5.59 | > 22.35 |
W3 | 11.17 | 11.17 | 11.17 | 5.59 | 5.59 | > 22.35 |
W4 | 11.17 | 11.17 | 11.17 | 5.59 | 5.59 | > 22.35 |
W5 | 10.39 | 10.39 | 10.39 | 5.19 | 5.19 | > 20.77 |
W6 | 5.19 | 5.19 | 5.19 | 5.19 | 5.19 | > 20.75 |
W7 | 11.44 | 11.44 | 11.44 | 5.72 | 5.72 | > 22.89 |
W8 | 11.44 | 11.44 | 11.44 | 11.44 | 5.72 | > 22.89 |
W9 | 11.61 | 11.61 | 11.61 | 11.61 | 5.81 | > 23.23 |
W10 | 11.61 | 11.61 | 11.61 | 5.81 | 5.81 | > 23.23 |
W11 | 12.00 | 12.00 | 12.00 | 6.00 | 6.00 | > 24.01 |
W12 | 10.38 | 10.38 | 10.38 | 10.38 | 5.19 | 7.08 |
W13 | 11.44 | 11.44 | 11.44 | 5.72 | 5.72 | > 22.89 |
W14 | 12.42 | 12.42 | 12.42 | 12.42 | 6.21 | > 24.84 |
W15 | 11.56 | 11.56 | 11.56 | 11.56 | 5.78 | 23.12 |
W16 | 11.56 | 11.56 | 11.56 | 11.56 | 5.78 | > 23.12 |
W17 | 11.56 | 11.56 | 11.56 | 11.56 | 5.78 | 4.12 |
W18 | 11.89 | 11.89 | 11.89 | 11.89 | 5.95 | > 23.78 |
W19 | 11.89 | 11.89 | 11.89 | 11.89 | 5.95 | > 23.78 |
W20 | 11.61 | 11.61 | 11.61 | 11.61 | 5.81 | 11.61 |
W21 | 10.39 | 10.39 | 10.39 | 10.39 | 5.19 | > 20.77 |
DMSO | NA | NA | NA | NA | NA | > 1.44 |
Broth control | NG | NG | NG | NG | NG | – |
Ofloxacin | 1.73 | 1.73 | 1.73 | – | – | – |
Fluconazole | – | – | – | 8.16 | 8.16 | – |
5-Florouracil | – | – | – | – | – | 7.69 |