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Table 3 In vitro anticancer screening of the synthesized compounds

From: Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives

Comp. Anticancer screening (IC50 = µM)
Cancer cell lines
HCT116 MCF7
1 221.5 > 246.1
2 288.7 > 288.7
3 > 236.7 > 236.7
4 > 253.8 > 253.8
5 > 236.9 > 236.9
6 > 285.1 74.1
7 > 277.0 207.7
8 203.8 > 279.2
9 > 310.2 263.7
10 192.8 262.9
11 > 276.8 > 276.8
12 221.4 83.0
13 > 253.8 > 253.8
14 71.8 193.4
15 > 260.4 > 260.4
5-Fluorouracil 12.7
Tamoxifen 4.3