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Table 4 Antioxidant activity of newly synthesized derivatives

From: Synthesis, SAR and in vitro therapeutic potentials of thiazolidine-2,4-diones

Compound % inhibition
25 μg/ml 50 μg/ml 75 μg/ml 100 μg/ml IC50 (μg/ml)
1 32.64 40.22 73.41 84.81 36.35
2 15.98 35.41 74.05 93.79 62.14
3 35.89 42.67 70.25 85.44 29.04
4 29.45 45.75 79.74 83.10 36.17
5 35.79 39.78 62.02 85.47 31.10
6 19.54 38.93 62.65 75.82 48.13
7 20.51 35.61 79.74 86.04 55.23
8 26.93 33.78 62.23 65.78 31.15
9 36.83 45.41 71.51 87.34 27.66
10 28.61 39.67 59.75 86.70 43.44
11 18.64 25.71 72.78 93.59 64.03
12 20.67 42.75 77.84 90.50 53.27
13 24.45 44.76 71.51 77.84 39.41
14 29.81 39.78 65.18 95.18 47.61
15 33.51 43.98 77.21 98.67 43.25
16 30.65 43.62 79.11 87.97 39.77
17 32.78 40.24 69.55 89.87 40.06
18 36.94 43.52 60.12 93.03 33.51
19 28.64 39.67 73.41 90.05 46.03
20 25.64 46.93 69.55 87.97 43.89
21 17.91 41.64 75.98 92.32 55.51
Ascorbic acid 38.99 55.78 72.51 93.15 21.64
  1. Compound numbers and their significant values are given in italic