Table 4 Antioxidant activity of newly synthesized derivatives
From: Synthesis, SAR and in vitro therapeutic potentials of thiazolidine-2,4-diones
Compound | % inhibition | ||||
|---|---|---|---|---|---|
25 μg/ml | 50 μg/ml | 75 μg/ml | 100 μg/ml | IC50 (μg/ml) | |
1 | 32.64 | 40.22 | 73.41 | 84.81 | 36.35 |
2 | 15.98 | 35.41 | 74.05 | 93.79 | 62.14 |
3 | 35.89 | 42.67 | 70.25 | 85.44 | 29.04 |
4 | 29.45 | 45.75 | 79.74 | 83.10 | 36.17 |
5 | 35.79 | 39.78 | 62.02 | 85.47 | 31.10 |
6 | 19.54 | 38.93 | 62.65 | 75.82 | 48.13 |
7 | 20.51 | 35.61 | 79.74 | 86.04 | 55.23 |
8 | 26.93 | 33.78 | 62.23 | 65.78 | 31.15 |
9 | 36.83 | 45.41 | 71.51 | 87.34 | 27.66 |
10 | 28.61 | 39.67 | 59.75 | 86.70 | 43.44 |
11 | 18.64 | 25.71 | 72.78 | 93.59 | 64.03 |
12 | 20.67 | 42.75 | 77.84 | 90.50 | 53.27 |
13 | 24.45 | 44.76 | 71.51 | 77.84 | 39.41 |
14 | 29.81 | 39.78 | 65.18 | 95.18 | 47.61 |
15 | 33.51 | 43.98 | 77.21 | 98.67 | 43.25 |
16 | 30.65 | 43.62 | 79.11 | 87.97 | 39.77 |
17 | 32.78 | 40.24 | 69.55 | 89.87 | 40.06 |
18 | 36.94 | 43.52 | 60.12 | 93.03 | 33.51 |
19 | 28.64 | 39.67 | 73.41 | 90.05 | 46.03 |
20 | 25.64 | 46.93 | 69.55 | 87.97 | 43.89 |
21 | 17.91 | 41.64 | 75.98 | 92.32 | 55.51 |
Ascorbic acid | 38.99 | 55.78 | 72.51 | 93.15 | 21.64 |