Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Table 6 In silico predicted LD₅₀ and toxicity profile of the synthesized sulfonamides 4a–f and 6a–f [70]

Compd. no	AMES toxicity	Carcinogenicity	Rat acute toxicity LD₅₀, (mol/kg)
4a			2.30
4b			2.30
4c			2.38
4d			2.29
4e			2.31
4f			2.34
6a			2.41
6b			2.34
6c			2.41
6d			2.35
6e			2.41
6f			2.36

ISSN: 2661-801X