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Table 6 In silico predicted LD50 and toxicity profile of the synthesized sulfonamides 4af and 6af [70]

From: Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1,2,3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative agents

Compd. no AMES toxicity Carcinogenicity Rat acute toxicity LD50, (mol/kg)
4a 2.30
4b 2.30
4c 2.38
4d 2.29
4e 2.31
4f 2.34
6a 2.41
6b 2.34
6c 2.41
6d 2.35
6e 2.41
6f 2.36