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Table 1 List of chemicals and materials

From: Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS

Namea Source
Dacomitinib LC Laboratories (MA, USA)
Acetonitrile (ACN, HPLC-grade), ammonium formate (NH4COOH), poly ethylene glycol 300 (PEG 300), dimethyl sulfoxide (DMSO), potassium cyanide (KCN) and formic acid (HCOOH) Sigma-Aldrich (USA)
Tween 80 Eurostar Scientific Ltd. (Liverpool, UK)
Water (HPLC grade) Milli-Q plus purification instrument (USA)
Sprague–Dawley ratsb The experimental animal care center at King Saud University (KSA)
  1. a All reference powders are of analytical grade and solvent are of HPLC grade
  2. b The University’s Ethics Review Committee approved the animal experimental design