Antimicrobial activities of saponins from Melanthera elliptica and their synergistic effects with antibiotics against pathogenic phenotypes

Table 4 Fractional inhibitory concentrations (FIC) calculated for the combination of reference antibiotics and compounds 1, 3 and 4 as a function of microorganisms

Microorganisms	Compound 1 + ATB^a		Compound 3 + ATB^a		Compound 4 + ATB^a
Microorganisms	∑ FIC	Interpretation	∑ FIC	Interpretation	∑ FIC	Interpretation
E. coli	0.2812	Synergy	0.132	Synergy	0.0664	Synergy
S. flexneri	0.515	Additive	0.257	Synergy	0.0331	Synergy
S. aureus	0.25	Synergy	0.531	Additive	0.0468	Synergy
C. parapsilosis	0.625	Additive	0.156	Synergy	0.187	Synergy
C. albicans	0.187	Synergy	0.0937	Synergy	0.125	Synergy
C. neoformans	0.187	Synergy	0.0937	Synergy	0.0781	Synergy

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