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Table 3 Antimicrobial activities of the reference antibiotics in the presence of compounds 1, 3 and 4 at 1/4 of MIC as a function of microorganisms

From: Antimicrobial activities of saponins from Melanthera elliptica and their synergistic effects with antibiotics against pathogenic phenotypes

Microorganisms ATBa alone ATBa with compound 1 at 1/4 of MIC ATBa with compound 3 at 1/4 of MIC ATBa with compound 4 at 1/4 of MIC
MIC MIC FIC MIC FIC MIC FIC
E. coli S2 (1) 32 1 0.0312 0.25 0.00781 0.125 0.00390
S. flexneri 16 0.25 0.0156 0.125 0.00781 0.0312 0.00195
S. aureus 2 0.125 0.0625 0.0625 0.0312 0.0312 0.0156
C. parapsilosis 0.5 0.25 0.50 0.0625 0.125 0.0312 0.0625
C. albicans 1 0.125 0.125 0.0625 0.0625 0.0625 0.0625
C. neoformans 2 0.125 0.0625 0.0625 0.0312 0.0312 0.0156
  1. MIC minimal inhibitory concentration, FIC fractional inhibitory concentration, ATB antibiotics
  2. aFluconazole for yeasts and tetracycline for bacteria; compounds 1, 3 and 4 were tested at the concentration of MIC/4 on the corresponding microorganism