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Table 2 Antimicrobial activities of the isolated compounds in the presence of reference antibioticsa at 1/4 of MIC as a function of microorganisms

From: Antimicrobial activities of saponins from Melanthera elliptica and their synergistic effects with antibiotics against pathogenic phenotypes

Microorganisms Compound 1 alone Compound 1 with ATBa at 1/4 of MIC Compound 3 alone Compound 3 with ATBa at 1/4 of MIC Compound 4 alone Compound 4 with ATBa at 1/4 of MIC
MIC MIC FIC MIC MIC FIC MIC MIC FIC
E. coli 32 8 0.25 128 16 0.125 256 16 0.0625
S. flexneri 16 8 0.5 64 16 0.25 128 4 0.0312
S. aureus 8 1 0.125 32 16 0.50 64 2 0.0312
C. parapsilosis 32 4 0.125 128 4 0.0312 16 2 0.125
C. albicans 64 4 0.0625 128 4 0.0312 16 1 0.0625
C. neoformans 16 2 0.125 32 2 0.0625 8 0.5 0.0625
  1. MIC minimal inhibitory concentration, FIC fractional inhibitory concentration, ATB antibiotics
  2. aFluconazole for yeasts and tetracycline for bacteria were tested at the concentration of MIC/4 on the corresponding microorganism