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Table 3 In vitro antimicrobial activity of the synthesized compounds

From: Design, synthesis and biological potential of heterocyclic benzoxazole scaffolds as promising antimicrobial and anticancer agents

Compound no. Antimicrobial results (MIC = µM)
Bacterial species Fungal species
BS SA EC ST KP AN CA
1 60.9 60.9 121.8 60.9 60.9 60.9 30.5
2 30.5 60.9 60.9 30.5 60.9 60.9 60.9
3 31.6 63.2 63.2 31.6 63.2 63.2 31.6
4 28.1 28.1 14.0 28.1 56.2 28.1 28.1
5 13.3 53.3 106.7 26.7 53.3 53.3 53.3
6 30.2 30.2 30.2 60.4 30.2 30.2 30.2
7 27.3 54.5 54.5 54.5 27.3 54.5 27.3
8 15.9 63.5 63.5 63.5 63.5 31.8 63.5
9 15.9 63.5 15.9 63.5 31.8 31.8 31.8
10 31.3 31.3 31.3 31.3 31.3 31.3 31.3
11 16.3 65.2 16.3 32.6 32.6 32.6 65.2
12 56.3 56.3 56.3 56.3 56.3 112.5 56.3
13 57.6 57.6 57.6 57.6 57.6 115.1 57.6
14 28.1 56.3 14.1 28.1 56.3 56.3 28.1
15 15.9 63.5 15.9 31.8 63.5 31.8 31.8
16 14.1 56.3 56.3 56.3 56.3 28.1 56.3
17 31.8 63.5 15.9 31.8 63.5 31.8 63.5
18 16.3 65.2 32.6 32.6 32.6 32.6 32.6
19 15.6 62.5 62.5 62.5 62.5 31.3 31.3
20 31.3 62.5 62.5 62.5 62.5 125.0 125.0
Ofloxacin 17.3 34.6 34.6 34.6 34.6
Fluconazole 40.8 40.8
  1. BS: Bacillus subtilis; SA: Staphylococcus aureus; EC: Escherichia coli; ST: Salmonella typhi; KP: Klebsiella pneumoniae; AN: Aspergillus niger; CA: Candida albicans