Table 3 Antimycobacterial activity, MIC and MLC of synthesized derivatives against M. tuberculosis H37Rv
Compound no. | Diameter of zone of inhibition (mm) against H37Rv (NCFT/TB/537) | MIC (µg/ml) | MLC (µg/ml) |
|---|---|---|---|
1 | > 20 | 12.5 | 25 |
2 | > 20 | 12.5 | 25 |
3 | > 20 | 12.5 | 25 |
4 | > 20 | 12.5 | 25 |
5 | 08 | 17.8 | 28.12 |
6 | > 20 | 12.5 | 25 |
7 | 10 | 15 | 28 |
8 | > 20 | 12.5 | 25 |
9 | 08 | 17.8 | 28.12 |
10 | > 20 | 12.5 | 25 |
11 | 10 | 15 | 28 |
12 | > 20 | 12.5 | 25 |
13 | > 20 | 12.5 | 25 |
14 | NA | NA | NA |
15 | > 20 | 12.5 | 25 |
16 | 10 | 15 | 28 |
17 | > 20 | 12.5 | 25 |
18 | > 20 | 12.5 | 25 |
19 | NA | NA | NA |
20 | 10 | 15 | 28 |
Streptomycin | > 20 | 12.5 | 25 |