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Table 25 In vitro cytotoxicity of most active compounds

From: Therapeutic potential of heterocyclic pyrimidine scaffolds

Compounds IC50 values (in µM)
A549 MCF7 DU145 HeLa
b26 4.1 ± 0.12 4.7 ± 0.18
b27 5.7 ± 0.22 24.7 ± 0.16 6.3 ± 0.21 22.7 ± 0.11
b28 4.2 ± 0.31 37.2 ± 0.31 5.8 ± 0.14 34.3 ± 0.32
5-Fluorouracil 1.3 ± 0.11 1.4 ± 0.09 1.5 ± 0.12 1.3 ± 0.14