Table 25 In vitro cytotoxicity of most active compounds
From: Therapeutic potential of heterocyclic pyrimidine scaffolds
Compounds | IC50 values (in µM) | |||
|---|---|---|---|---|
A549 | MCF7 | DU145 | HeLa | |
b26 | 4.1 ± 0.12 | – | 4.7 ± 0.18 | – |
b27 | 5.7 ± 0.22 | 24.7 ± 0.16 | 6.3 ± 0.21 | 22.7 ± 0.11 |
b28 | 4.2 ± 0.31 | 37.2 ± 0.31 | 5.8 ± 0.14 | 34.3 ± 0.32 |
5-Fluorouracil | 1.3 ± 0.11 | 1.4 ± 0.09 | 1.5 ± 0.12 | 1.3 ± 0.14 |