Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Table 5 Antiurease activity of synthesized compounds (3a–k and 3l–p)

Entry	Compound no	Percentage inhibition at 50 µg/ml
1	3a	58.8 ± 0.58
2	3b	67.7 ± 0.77
3	3c	48.9 ± 0.65
4	3d	54.7 ± 0.67
5	3e	42.9 ± 0.45
6	3f	40.3 ± 0.40
7	3g	34.2 ± 0.38
8	3h	38.8 ± 0.45
9	3i	36.9 ± 0.45
10	3j	52.1 ± 0.78
11	3k	64.2 ± 0.87
12	Thiourea	95.6 ± 0.87

The results are average ± SD of triplicate experiments p < 0.05. Thiourea used as positive control

ISSN: 2661-801X