Skip to main content

Advertisement

Table 5 Antiurease activity of synthesized compounds (3ak and 3lp)

From: Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Entry Compound no Percentage inhibition at 50 µg/ml
1 3a 58.8 ± 0.58
2 3b 67.7 ± 0.77
3 3c 48.9 ± 0.65
4 3d 54.7 ± 0.67
5 3e 42.9 ± 0.45
6 3f 40.3 ± 0.40
7 3g 34.2 ± 0.38
8 3h 38.8 ± 0.45
9 3i 36.9 ± 0.45
10 3j 52.1 ± 0.78
11 3k 64.2 ± 0.87
12 Thiourea 95.6 ± 0.87
  1. The results are average ± SD of triplicate experiments p < 0.05. Thiourea used as positive control