Table 4 Antibacterial activity of synthesized compounds (3a–k and 3l–p) against Gram positive and Gram negative bacteria
Entry | Product no | % inhibition (50 μg/ml) | ||||
|---|---|---|---|---|---|---|
P. aeruginosa | B. subtilis | E. coli | S. aureus | S. typhi | ||
1 | 3a | 67.3 ± 0.76 | *** | 94.5 ± 0.09 | 33.9 ± 0.37 | 27.6 ± 0.08 |
2 | 3b | 39.2 ± 0.45 | *** | 50.1 ± 0.29 | 9.57 ± 0.15 | 5.58 ± 0.05 |
3 | 3c | *** | *** | *** | *** | *** |
4 | 3d | 34.9 ± 0.27 | *** | 7.8 ± 0.09 | *** | 8.34 ± 0.23 |
5 | 3e | *** | *** | *** | *** | ** |
6 | 3f | *** | *** | *** | *** | *** |
7 | 3g | *** | *** | *** | *** | *** |
8 | 3h | 37.6 ± 0.26 | *** | 50.4 ± 0.45 | *** | 12.0 ± 0.02 |
9 | 3i | 41.1 ± 0.47 | *** | 70.4 ± 0.78 | *** | 2.59 ± 0.01 |
10 | 3j | *** | *** | *** | *** | *** |
11 | 3k | 50.5 ± 0.58 | *** | 72.5 ± 0.87 | 20.1 ± 0.06 | 17.3 ± 0.05 |
12 | 3Â l | *** | *** | *** | *** | *** |
13 | 3m | *** | *** | *** | *** | *** |
14 | 3n | 20.8 ± 0.17 | *** | 30.6 ± 0.26 | *** | * |
15 | 3o | *** | *** | *** | *** | *** |
16 | 3p | *** | *** | *** | *** | *** |
17 | Control | 100 ± 1.28 | 100 ± 1.21 | 100 ± 1.01 | 100 ± 0.99 | 100 ± 0.99 |