Scheme 1From: Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitorsReactions and conditions: a appropriate substituted 2-chloro-N-phenylacetamide, CH3CN anhydrous, K2CO3, 80 °C, 6–7 h; b appropriate (substituted)-phenylboronic acid, (CH3COO)2Cu, EtN3, CH2Cl2 Back to article page