Table 21 Cyclooxygenase inhibition activity of synthesized compound
From: Biological potential of thiazolidinedione derivatives of synthetic origin
Compounds | Concentration (Um) (no. of experiments) | COX-1 activity (% inhibition) | COX-2 activity (% inhibition) |
|---|---|---|---|
71 | 10 (3) | 28.4 ± 11.6 | 19.4 ± 8.2 |
72 | 10 (3) | 26.5 ± 6 | 13.6 ± 1.1 |
Celecoxib | 10 (3) | 0.3 ± 2.5 | 30.8 ± 5.9 |