Table 2 Precision, accuracy, recovery, and ME for lesinurad for samples in rat plasma (n = 6)
From: Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay
Concentration (ng/mL) | Intra-day | Inter-day | Recovery (%) | ME (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | RSD (%) | RE (%) | Accuracy (%) | Mean ± SD | RSD (%) | RE (%) | Accuracy (%) | |||
50 | 54.81 ± 4.6 | 8.46 | 4.88 | 109.62 | 56.70 ± 3.6 | 6.38 | 2.85 | 113.4 | – | – |
100 | 93.98 ± 7.8 | 8.25 | 3.37 | 93.98 | 99.26 ± 6.4 | 6.43 | 2.64 | 99.26 | 106.87 | 101.95 |
1000 | 942.97 ± 64.4 | 6.83 | 2.79 | 94.30 | 932.26 ± 11.6 | 1.24 | 0.05 | 93.23 | 98.94 | 109.19 |
25,000 | 25,481.66 ± 525.4 | 2.06 | 0.84 | 101.93 | 25732.98 ± 2005.4 | 7.79 | 0.01 | 102.93 | 101.12 | 107.21 |