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Table 4 The EC50 values of 5d, 5f, 5i and 5m against TMV

From: Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold

Compd.

TMV

Regression equation

r

EC50 (µg/mL)

500 μg/mL

250 μg/mL

3d

59.8 ± 6.2

55.2 ± 4.4

y = 0.473x − 3.967

0.98

152.8 ± 3.2

3f

68.4 ± 7.4

64.2 ± 8.8

y = 0.744x − 3.512

0.99

99.7 ± 2.7

3i

66.8 ± 9.8

63.3 ± 5.8

y = 0.816x + 3.823

0.99

127.1 ± 2.6

3m

57.1 ± 9.6

52.3 ± 8.5

y = 0.361x + 4.197

0.99

167.3 ± 4.8

Ningnanmycin a

51.3 + 2.6

50.3 + 3.8

y = 0.203x + 4.154

0.97

211.1 ± 3.6

  1. Average of three replicates
  2. aThe commercial agricultural antiviral agent ningnanmycin was used for comparison of antiviral activity