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Table 4 The EC50 values of 5d, 5f, 5i and 5m against TMV

From: Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold

Compd. TMV Regression equation r EC50 (µg/mL)
500 μg/mL 250 μg/mL
3d 59.8 ± 6.2 55.2 ± 4.4 y = 0.473x − 3.967 0.98 152.8 ± 3.2
3f 68.4 ± 7.4 64.2 ± 8.8 y = 0.744x − 3.512 0.99 99.7 ± 2.7
3i 66.8 ± 9.8 63.3 ± 5.8 y = 0.816x + 3.823 0.99 127.1 ± 2.6
3m 57.1 ± 9.6 52.3 ± 8.5 y = 0.361x + 4.197 0.99 167.3 ± 4.8
Ningnanmycin a 51.3 + 2.6 50.3 + 3.8 y = 0.203x + 4.154 0.97 211.1 ± 3.6
  1. Average of three replicates
  2. aThe commercial agricultural antiviral agent ningnanmycin was used for comparison of antiviral activity