Table 2 Cytotoxicity of selected compounds against a panel of cell strains
From: Synthesis and anticancer activity of novel quinazolinone-based rhodanines
| |||||
|---|---|---|---|---|---|
Code | R1 | R2 | Cell line | ||
HL-60 | K-562 | AG01523 | |||
37 | 4-CF3 | H | 5.5 (± 0.2) | 5.0 (± 3.2) | > 100 |
43 | 4-Cl | OCH3 | 5.1 (± 2.0) | 4.5 (± 4.3) | > 100 |
45 | 4-Br | OCH3 | 1.2 (± 0.5) | 1.5 (± 0.2) | > 100 |
47 | 4-CF3 | OCH3 | 2.6 (± 0.4) | 5.1 (± 0.3) | > 100 |
Doxorubicin | – | – | 0.011 (± 0.006) | 0.212 (± 0.074) | 0.875 (± 0.248) |
