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Table 2 Cytotoxicity of selected compounds against a panel of cell strains

From: Synthesis and anticancer activity of novel quinazolinone-based rhodanines

Code R1 R2 Cell line
HL-60 K-562 AG01523
37 4-CF3 H 5.5 (± 0.2) 5.0 (± 3.2) > 100
43 4-Cl OCH3 5.1 (± 2.0) 4.5 (± 4.3) > 100
45 4-Br OCH3 1.2 (± 0.5) 1.5 (± 0.2) > 100
47 4-CF3 OCH3 2.6 (± 0.4) 5.1 (± 0.3) > 100
Doxorubicin 0.011 (± 0.006) 0.212 (± 0.074) 0.875 (± 0.248)
  1. IC50s (μM), mean of three independent experiments (± standard deviation)