Table 4 Synthesis of N,N-diethylamides 17–23
From: Formation of amides: one-pot condensation of carboxylic acids and amines mediated by TiCl4
Entry | R1 | R2 | R3 | Product | Yield (%)a | |
|---|---|---|---|---|---|---|
q | C6H5 | C2H5 | C2H5 | 17 |
| 64 |
r | 4-NO2–C6H4 | C2H5 | C2H5 | 18 |
| 80 |
s | 4-CH3O–C6H4 | C2H5 | C2H5 | 19 |
| 56 |
t | 4-Cl–C6H4 | C2H5 | C2H5 | 20 |
| 77 |
u | C6H5CH2 | C2H5 | C2H5 | 21 |
| 85 |
v | C6H5CH=CH | C2H5 | C2H5 | 22 |
| 87 |
w | C15H31 | C2H5 | C2H5 | 23 |
| 91 |
