Fig. 2

Gross appearance of gastric mucosa in rats: a pre-treated with saline, 10 mL/kg (ulcer control). Severe injuries are seen, as absolute ethanol (1 mL/100 g) produced excessive visible hemorrhagic necrosis in gastric mucosa b and c pre-treated with compound 5a at doses of 100 and 500 µg/kg, d and e pretreated with compound 5b at doses of 100 and 500 µg/kg, f and g pre-treated with compound 5c at doses of 100 and 500 µg/kg, h and i pre-treated with compound 5d at doses of 100 and 500 µg/kg, j and k pre-treated with compound 5e at doses of 100 and 500 µg/kg, l and m pre-treated with compound 5f at doses of 100 and 500 µg/kg and n pre-treated with omeprazole 30 mg/kg. The injuries reduce with increase of compounds doses and omeprazole, compared to ulcer control