Table 4 Antibacterial and antifungal activity of compounds 2, 3, and 4 (diameter of inhibition zone is given in mm)
A) Antifungal activity | ||||
|---|---|---|---|---|
Tested pathogen | FUNGI | |||
A. fumigates | S. racemosum | G. candidum | Candida albicans | |
Amphotericin B | ||||
Reference compound | 23.7 ± 0.1 | 19.7 ± 0.2 | 28.7 ± 0.2 | 25.4 ± 0.1 |
2 | 16.2 ± 0.4 | 15.0 ± 0.4 | 17.6 ± 0.6 | NA |
3 | 21.3 ± 0.4 | 17.2 ± 0.2 | 24.6 ± 0.6 | NA |
4 | 17.6 ± 0.6 | 15.4 ± 0.3 | 12.6 ± 0.4 | NA |
B) Antibacterial activity | ||||
|---|---|---|---|---|
Tested pathogen | Gram positive bacteria | Gram negative bacteria | ||
S. pneumoniae | B. subtilis | P. aeruginosa | E. coli | |
Ampicillin | Gentamicin | |||
Reference compounds | 23.8 ± 0.2 | 32.4 ± 0.3 | 17.3 ± 0.1 | 19.9 ± 0.3 |
2 | 16.9 ± 0.6 | 18.2 ± 0.4 | NA | 11.9 ± 0.6 |
3 | 18.2 ± 0.1 | 20.3 ± 0.1 | NA | 20.3 ± 0.1 |
4 | 12.3 ± 0.6 | 12.7 ± 0.4 | NA | 8.5 ± 0.4 |