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Table 3 In-vitro anti-bacterial activity data of complexes 1–4

From: Synthesis, crystallographic, spectroscopic studies and biological activity of new cobalt(II) complexes with bioactive mixed sulindac and nitrogen-donor ligands

Compounds

Bordetella

E. coli

S. epi

S. aureus

Candida

Saccharomyces

G-

G-

G+

G+

Yeast

Yeast

(1)

15.3 ± 0.5

10.1 ± 0.4

21.0 ± 0.4

19 ± 1

–

–

(2)

13 ± 1

–

23 ± 1

11 ± 1

–

–

(3)

12 ± 2

8.5 ± 1.5

26.7 ± 0.6

21 ± 1

–

–

(4)

16 ± 2

12 ± 2

39 ± 1

25.0 ± 1.5

42 ± 1

41.12 ± 0.5

CoCl2

22 ± 2

12 ± 2

30.0 ± 0.5

11 ± 1

20.0 ± 0.7

22 ± 1

Sulindac

–

–

–

–

–

–

Genta.

30 ± 1

37 ± 1

28 ± 1

32.7 ± 0.6

–

–

Nes.

–

–

–

–

35.5 ± 0.2

40.5 ± 0.4

  1. Inhibition zone diameter (IZD) in mm, all microorganisms were resistant to DMSO. The data stated as average ± standard deviation (N = 3), the concentration of the complexes and the standards was 30 mg/5 mL in DMSO (6 g/l)
  2. — dashes indicated zero inhibition