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Table 2 Antimicrobial activity (MIC = µM/ml) of the synthesized analogous

From: Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a]pyrimidine derivatives

Comp. Minimum inhibitory concentration (MIC)
Bacterial strains Fungal strains
S. aureus B. subtilis E. coli C. albicans A. niger
1 2.19 2.19 2.19 2.19 1.09
2 4.19 2.10 2.10 1.05 1.05
3 2.27 2.27 2.27 1.13 1.13
4 4.33 4.33 8.67 2.17 1.08
5 9.07 1.13 9.07 2.27 1.13
6 2.27 2.27 2.27 2.27 1.13
7 2.28 1.14 2.28 2.28 1.14
8 2.39 2.39 2.39 2.39 1.20
9 2.26 2.26 2.26 2.26 1.13
10 2.18 2.18 2.18 2.18 1.09
11 2.33 1.17 2.33 2.33 1.17
12 2.14 2.14 2.14 2.14 2.14
13 9.33 2.33 9.33 2.33 2.33
14 2.14 2.14 2.14 2.14 2.14
15 4.16 1.04 2.08 1.04 1.04
16 4.66 1.17 2.33 2.33 2.33
17 2.34 1.17 2.34 2.34 1.17
18 4.63 0.58 2.31 2.31 2.31
19 2.47 1.24 2.47 2.47 1.24
20 2.31 1.16 2.31 1.16 2.31
21 2.21 1.10 1.10 1.10 1.10
22 2.39 2.39 2.39 1.20 1.20
23 4.63 1.16 2.31 2.31 2.31
24 2.35 1.17 2.35 1.17 1.17
Std. 0.47a 0.47a 0.47a 0.50b 0.50b
  1. aNorfloxacin
  2. bFluconazole