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Table 1 The physicochemical properties of the synthesized analogous

From: Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a]pyrimidine derivatives

Comp. M. Formula M. Wt. m.p. (°C) R f valuea % yield
1 C30H28N4O8 572 121–123 0.58 86
2 C29H32N4O10 596 169–171 0.31 83
3 C26H25N5O9 551 159–161 0.53 80
4 C30H35N5O7 577 150–153 0.68 84
5 C26H25N5O9 551 122–124 0.63 91
6 C26H25N5O9 551 159–161 0.51 64
7 C28H31N5O7 549 161–163 0.56 88
8 C26H26N4O8 522 170–172 0.61 84
9 C27H28N4O9 552 146–148 0.41 80
10 C26H24Cl2N4O7 574 148–150 0.42 83
11 C27H28N4O8 536 174–176 0.45 78
12 C26H25BrN4O7 584 144–146 0.66 72
13 C27H28N4O8 536 148–150 0.39 78
14 C26H25BrN4O7 584 155–157 0.38 72
15 C26H25BrN4O8 601 119–121 0.62 90
16 C27H28N4O8 536 149–151 0.47 91
17 C27H26N4O8 534 140–142 0.25 79
18 C26H25ClN4O7 540 150–153 0.59 73
19 C26H26N4O7 506 144–146 0.47 83
20 C26H25ClN4O7 540 151–153 0.55 75
21 C28H30N4O9 566 146–148 0.66 85
22 C26H26N4O8 522 100–102 0.61 74
23 C26H25ClN4O7 540 141–143 0.56 77
24 C28H28N4O7 532 143–145 0.53 81
  1. aTLC mobile phase-Benzene