Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a]pyrimidine derivatives

BMC Chemistry

Table 1 The physicochemical properties of the synthesized analogous

Comp.	M. Formula	M. Wt.	m.p. (°C)	R_f value^a	% yield
1	C₃₀H₂₈N₄O₈	572	121–123	0.58	86
2	C₂₉H₃₂N₄O₁₀	596	169–171	0.31	83
3	C₂₆H₂₅N₅O₉	551	159–161	0.53	80
4	C₃₀H₃₅N₅O₇	577	150–153	0.68	84
5	C₂₆H₂₅N₅O₉	551	122–124	0.63	91
6	C₂₆H₂₅N₅O₉	551	159–161	0.51	64
7	C₂₈H₃₁N₅O₇	549	161–163	0.56	88
8	C₂₆H₂₆N₄O₈	522	170–172	0.61	84
9	C₂₇H₂₈N₄O₉	552	146–148	0.41	80
10	C₂₆H₂₄Cl₂N₄O₇	574	148–150	0.42	83
11	C₂₇H₂₈N₄O₈	536	174–176	0.45	78
12	C₂₆H₂₅BrN₄O₇	584	144–146	0.66	72
13	C₂₇H₂₈N₄O₈	536	148–150	0.39	78
14	C₂₆H₂₅BrN₄O₇	584	155–157	0.38	72
15	C₂₆H₂₅BrN₄O₈	601	119–121	0.62	90
16	C₂₇H₂₈N₄O₈	536	149–151	0.47	91
17	C₂₇H₂₆N₄O₈	534	140–142	0.25	79
18	C₂₆H₂₅ClN₄O₇	540	150–153	0.59	73
19	C₂₆H₂₆N₄O₇	506	144–146	0.47	83
20	C₂₆H₂₅ClN₄O₇	540	151–153	0.55	75
21	C₂₈H₃₀N₄O₉	566	146–148	0.66	85
22	C₂₆H₂₆N₄O₈	522	100–102	0.61	74
23	C₂₆H₂₅ClN₄O₇	540	141–143	0.56	77
24	C₂₈H₂₈N₄O₇	532	143–145	0.53	81

ISSN: 2661-801X