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Table 3 Analysis of variance for the experimental results of zerumbone content from Z. zerumbet rhizomes

From: Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts

Parameter

Estimated coefficient

Standard error

Degree of freedom

Sum of squares

F value

Prob > F

Model intercept B0

5.51

0.084

14

3.95

13.38

0.0001

Linear

 X1

0.14

0.042

1

0.25

11.74

0.005

 X2

0.017

0.042

1

0.00343

0.16

0.693

 X3

−0.055

0.042

1

0.037

1.77

0.211

 X4

0.27

0.042

1

0.085

40.46

0.0001

Quadratic

 \(X_{1}^{2}\)

−0.41

0.063

1

0.89

42.02

0.0001

 \(X_{2}^{2}\)

−0.096

0.063

1

0.05

2.35

0.1513

 \(X_{3}^{2}\)

−0.085

0.063

1

0.039

1.84

0.2001

 \(X_{4}^{2}\)

−0.39

0.063

1

0.081

38.52

0.0001

Interaction

 X1X2

0.12

0.073

1

0.057

2.71

0.1259

 X1X3

0.14

0.073

1

0.079

3.74

0.077

 X1X4

−0.31

0.073

1

0.039

18.45

0.001

 X2X3

0.45

0.073

1

0.08

37.78

0.0001

 X2X4

−0.13

0.073

1

0.072

3.42

0.0894

 X3X4

−0.061

0.073

1

0.015

0.69

0.4212

Lack of fit

  

10

0.23

2.15

0.3596

Pure error

  

2

0.022

  

Residual

  

12

0.025

  

R2 adjusted

    

0.875

 

R2

    

0.939

 

C.V.%

2.86

     

Corr. total

  

26

4.21

  
  1. X1, ethanol concentration; X2, microwave power; X3, irradiation time; X4, liquid-to-solid ratio