Fig. 2
Heat changes as a function of the total Casiopeína III-ia concentration in the calorimetric cell from ITC measurements carried out in two aqueous media. Circles correspond to the solute dissolved in the phosphate 0.1 M and pH 7.4 media and titrated into the same buffer while squares represent the solute dissolved in pure water and titrated into the same solvent. The lines correspond to the calculated heat changes using optimized values of K D , ∆H D and the stoichiometry of the aggregate formation equilibria (χ 2 = 0.0513 for Casiopeína dissolved in the phosphate media and χ 2 = 0.086 for Casiopeína dissolved in pure water)