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Table 1 Comparison of yields of 4d through methods with or without microwave irradiation

From: Microwave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties

Entry Solvent Method Time (min) Temperature/°C Yield/ %
1 EtOH No-MW 300 r.t. 90
2 EtOH No-MW 120 Reflux 85
3 EtOH MW 1 78 68
4 EtOH MW 5 78 80
5 EtOH MW 10 78 92
6 EtOH MW 15 78 92
7 EtOH MW 10 70 78
8 EtOH MW 10 85 91