Skip to main content

Table 2 Analytical performance data for the proposed approaches

From: Determination of adapalene in gel formulation by conventional and derivative synchronous fluorimetric approaches. Application to stability studies and in vitro diffusion test

Parameters The first approach at 389 nm The second approach
SDSF at 346 nm FDSF at 312.45 nm
Linearity range (ng/mL) 2.0–14.0 2.0–14.0 2.0–14.0
Intercept (a) −4.714 −1.212 5.171
Slope (b) 35.357 3.975 3.729
Correlation coefficient (r) 0.9999 0.9998 0.9998
SD of residuals (S y/x ) 1.59 0.34 0.31
SD of intercept (S a ) 1.34 0.29 0.26
SD of slope (S b ) 0.15 0.03 0.03
Percentage relative standard deviation, % RSD 0.42 0.88 0.76
Percentage relative error, % error 0.16 0.33 0.29
Limit of detection, LOD (ng/mL) 0.13 0.24 0.23
Limit of quantitation, LOQ (ng/mL) 0.38 0.73 0.69