Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives of nitro-l-arginine methyl ester

BMC Chemistry

Table 8 Antifungal effect expressed as MIC and MFC values (mg/mL) of 6a–j

Sample	C. albicans ATCC 10231		C. glabrata ATCC MYA 2950		C. parapsilosis ATCC 22019
Sample	MIC^a	MFC^a	MIC^a	MFC^a	MIC^a	MFC^a
6a	0.6	1.25	1.25	1.25	0.003	0.003
6b	0.6	1.25	2.5	10	0.003	0.003
6c	0.6	0.6	10	10	0.003	0.003
6d	0.3	1.25	0.6	2.5	0.003	0.003
6e	10	10	10	10	5	5
6f	0.6	0.6	2.5	5	0.003	0.003
6g	0.3	1.25	1.25	2.5	0.003	0.003
6h	0.3	5	10	10	0.003	0.003
6i	0.03	10	10	10	10	10
6j	0.3	1.25	1.25	1.25	0.003	0.003
5	1.25	1.25	0.6	2.5	0.003	0.003
N	0.004	0.008	0.004	0.008	0.004	0.008

ISSN: 2661-801X