Fig. 7

Effect of varying the magnitude of the galvanostatic current on the CA3-CA1 response. Each data point is the average current response of 6 sensors averaged over 0.05–0.15 s. The error bars are one standard deviation. The overlayer was treated with 1 mg/mL OX0245 in 0.4 M AMPSO (pH 9.5), 1 M NaCl, 1 % TX-100 and 0.5 % Surfynol 465. 7 uL of saliva obtained from one donor was applied to each sensor. The electrochemical protocol was as follows: 5 s wait time, CA1 at −0.2 V for 2 s, CA2 at −0.04 V for 0.5 s, galvanostatic current of 0–300 nA for 5 s, followed by CA3 at −0.2 V for 2 s